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Who should read this page?
1. Anyone working with Metabolites
2. Anyone working with polar compounds
3. Anyone who is looking to increase
throughput in LCMS
4. Anyone Interested in learning new ways to
do HPLC
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 Ordering Information
Each Kit Contains:
1 Cogent Diamond Hydride™
2 Cogent Bidentate C18™
Available in most column sizes
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If you are frustrated with analysis of hydrophilic metabolites from serum, plasma, urine, saliva or any biological fluid, this
column kit is for you. Cogent TYPE-C™ silica HPLC columns were introduced in March of 1992 and there have been many great
applications for our silica hydride based approach to column technology. However, there has been no greater interest then the bio
analytical application for metabolomics.
Using the two columns in this kit, our unique Cogent Diamond Hydride™ column for all hydrodphilic and many hydrophobic
metabolites and our Cogent Bidentate C18™ for remaining hydrophobic species, you can easily retain all metabolites using
LCMS. Using both Aqueous Normal Phase (ANP) and Reverse Phase (RP) with these columns you can separate both positive and negative
species and with the incredible precision that silica hydride columns provide, very accurate “metabolomes” can be produced as
reported by Rhee et al.
Precise enough for plotting accurate mass v. retention time, you can identify unknown metabolites or differences between healthy
and diseases organisms or cells.
The Metabolomics kit also offers a special discount from list price compared to purchasing these columns separately.
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