RSA™ Reduced Surface Activity Glass for Vials & Inserts

RSA Glass™ - Reduced Surface Activity Glass
This next generation of glass reduces the interaction between analytes and its surface.
The table below illustrates the impact of RSA (Reduced Surface Activity) Glass for HPLC and GC autosamplers vials. It compares data on sample adsorbance to the glass surface and pH changes over a 4 hour period.

The green highlighted data on the chart below compares different brands of glass vials available in the market today and their ability to adsorb certain compounds. If these compounds are in low abundance and lost to the glass it will greatly skew your data compared to compounds in RSA Glass vials.

Adsorption Methodology Synopsis: A test solution with a concentration of 5ug/ml was placed in 3 vials from each of the brands listed below and labeled: N1, N2 & N3. After 4 hours in the vials: the final concentration and the concentration changes due to adsorption to the vial were quantified by HPLC for each vial in the study. The final concentration results are reported as N1, N2 & N3 with an average (AVG) for each vial brand reported. The percent loss was calculated and reported as (% Loss). Notice the difference between RSA Glass vials and other market brands to determine the value and benefits of using RSA Glass.

The second data illustration on the chart below is highlighted in yellow and illustrates how leading vial brands on the market today may change the sample diluents’ pH due to the glass surface chemistry compared to RSA vials.

pH Methodology Synopsis: DI water placed in the same vial brands as noted above had pH data points taken at the start of the testing analysis and during a consecutive 4 hour period. The data shown in yellow are the ending pH readings. Note the starting pH of DI water was 5.45. This simple test and other more extensive tests have shown that vials made with RSA Glass will not cause changes in the sample pH even after 4 hours. Other brands including market leaders can cause changes by more than 1.25 pH units under the same conditions.

Ordering Info

Adsorption & pH Changes

Green = Sample Adsorption Test
Yellow = pH Change Test

	N1	N2	N3	AVG	% Loss	pH

Starting Points	287.8	287	286.1	287	0.00	5.45

RSA Glass™	283.5	287.2	287.2	286	0.35	5.50

MicroSolv™ Brand	234.9	235.2	239.1	236	17.62	6.15

Basik Vials™	157.7	158.7	159.9	159	44.67	6.00

Brand F	114.3	223.2	57.3	132	54.14	6.65

Brand N	168.8	149.9	146.5	155	45.96	6.94

Starting Points: Adsorption Test; 5ug/ml Chlorhexidene in water; pH Test; DI Water pH 5.45.
RSA Glass Vials: Reduced Surface Activity Glass Vials.
MicroSolv Brand Vials: our leading line of autosampler vials and inserts on the market today. Made with pharmaceutical grade glass.
Basik Brand Vials: our popular brand of economy autosampler vials for when quality issues are mostly limited to fit and form.
Brand “F”: a leading brand of autosampler vials that is resold by many laboratory supply dealers.
Brand “N” is the leading brand of autosampler vials that is sold through dealers and private labeled some of the largest instrument companies.

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